David M. Geiser, Ph.D.
- B.A., Ecology and Evolutionary Biology, Northwestern University
- Ph.D., Genetics, University of Georgia
Areas of Interest
Molecular evolutionary genetics of pathogenic and toxigenic fungi
Research in my lab focuses on the molecular evolutionary genetics of fungi, mostly in the realm of molecular phylogenetics and systematics at the species level. We apply these tools mostly to identify and better understand the fungal culprits in plant and animal diseases and toxicoses. Unfortunately, identifying fungi using traditional micromorphological tools is very difficult, and tends to lead to species concepts that are too broad. We use the tools of multilocus molecular phylogenetics to recognize and identify species, which provides a much more objective and reliable framework for understanding the biology of these fungi.
As Director of the Fusarium Research Center at Penn State, I also curate the world's largest collection of cultures of Fusarium, one of the most important genera of toxigenic and pathogenic fungi. We are nearing 20,000 accessions and provide isolates to certified researchers, and also provide identification and other services. Most of the research in my lab naturally involves this important genus, but I am also involved in projects in a variety of other fungi.
Shroers H-J, Samuels GJ, Zhang N, Short DPG, Juba JH, Geiser DM. 2016. Epitypification of Fusisporium (Fusarium) solani and its assignment to a common phylogenetic species in the Fusarium solani Species Complex. Mycologia doi 10.3852/15-255.
O’Donnell K, Ward TJ, Robert VARG, Crous PW, Geiser DM, Kang S. 2015. DNA sequence-based identification of Fusarium: Current status and future directions. Phytoparasitica 43: 583-595.
O’Donnell K, Sink S, Libeskind-Hadas R, Hulcr J, Kasson MT, Ploetz RC, Konkol JL, Ploetz JN, Carrillo D, Campbell A, Duncan RE, Liyanage PNH, Eskalen A, Na F, Geiser DM, Bateman C, Freeman S, Mendel Z, Sharon M, Aoki T, Cossé AA, Rooney AP. 2015 Discordant phylogenies suggest repeated host shifts in the Fusarium-Euwallacea ambrosia beetle mutualism. Fungal Genetics and Biology 82: 277-290.
Araújo JPM, Evans HC, Geiser DM, Mackay WP, Hughes DP. 2015. Uravelling the diversity behind the Ophiocordyceps unliateralis (Ophiocordycipitaceae) complex: Three new species of zombie-ant fungi from the Brazilian Amazon. Phytotaxa 220: 224-238.
Geiser DM. 2015. Antifungal design: The toxicity-resistance yin-yang. (invited News and Views) Nature Chemical Biology 11: 453-454.
Montecchio M, Faccoli M, Short DPG, Fanchin M, Geiser DM, Kasson MT. 2015. First report of Fusarium solani phylogenetic species 25 associated with early stages of Thousand Cankers Disease on Juglans nigra and Juglans regia in Italy. Plant Disease 99: 1183.
Guo L, Blatt AZ, Geiser DM, Jiménez-Gasco MM, Kuldau GA. 2015. Mating type and spore killing characterization of Fusarium verticillioides strains. Mycological Progress 14: 1-6.
De Hoog CS, Chaturvedi V, Denning DW, Dyer PS, Frisvad JC, Geiser DM, Gräser Y, Guarro J, Haase G, Kwon-Chung KJ, Meis JF, Meyer W, Pitt JI, Samson RA, Taylor JW, Tintelnot K, Vitale RG, Walsh TJ, Lackner M. 2015. Name changes in medically important fungi and the implications for clinical practice. J. Clin. Microbiol. 53: 1056-1062.
Elmore MH, McGary KL, Wisecaver JH, Slot JC, Geiser DM, Sink S, O’Donnell K, Rojas A. 2015. Clustering of two genes putatively involved in cyanate detoxification evolved recently and independently in multiple fungal lineages. Genome Biology and Evolution 7: 789-800.
Aoki T, Vaughan MM, McCormick SP, Busman M, Ward TJ, Kelly A, O’Donnell K, Geiser DM. 2015. Fusarium dactydilis sp. nov., a novel nivalenol toxin-producing species sister to F. pseudograminearum isolated from orchard grass (Dactylis glomerata) in Oregon and New Zealand. Mycologia 107: 409-418.
Geiser DM, LoBuglio KF, Gueidan C. 2015. Pezizomycotina: Eurotiomycetes. Pp 121-141 in The Mycota VII, Systematics and Evolution, Part B. Second Edition. McLaughlin DJ, Spatafora JW, Lemke PA, eds. Springer, Berlin Heidelberg.
Aoki T, O’Donnell K, Geiser DM. 2014. Systematics of key phytopathogenic Fusarium species: current status and future challenges. J. Gen. Plant Path. 80: 189-201.
Short DPG, O’Donnell K, Geiser DM. 2014. Clonality, recombination, and hybridization in the plumbing-inhabiting human pathogen Fusarium keratoplasticum inferred from multilocus sequence typing. BMC Evolutionary Biology 14:91.
Park B, Martin F, Geiser DM, Kim HS, Mansfield MA, Nikolaeva E, Park SY, Coffey MD, Russo J, Kim SH, Balci Y, Agad G, Burgess T, Grunwald NJ, Cheong K, Choi J, Lee YH, Kang S. 2013. Phytophthora Database 2.0: Update and Future Direction. Phytopathology 103: 1204-1208.
Ma L, Geiser DM, Proctor RH, Rooney AP, O'Donnell K, Trail F, Gardiner DM, Manners JM, Kazan K. 2013. Fusarium Pathogenomics. Annu. Rev. Microbiol. 67: 399-416.
Kasson MP, O'Donnell K, Rooney AP, Sink S, Ploetz RC, Ploetz JN, Konkol JL, Carrillo D, Freeman S, Mendel Z, Smith JA, Black AW, Hulcr J, Bateman C, Stefkova K, Campbell PR, Geering ADW, Dann EK, Esklalen A, Mohotti K, Short DPG, Aoki T, Fenstermacher KA, Davis DD, Geiser DM. 2013. An inordinate fondness for Fusarium: Phylogenetic diversity of fusaria cultivated by ambrosia beetles in the genus Euwallacea on avocado and other plant hosts. Fungal Genetics and Biology. 56: 147-157.
Short DPG, O'Donnell K, Thrane U, Fog Nielsen K, Zhang N, Juba JH, Geiser DM. 2013. Phylogenetic relationships among members of the Fusarium solani species complex in human infections, and the descriptions of F. keratoplasticum sp. nov. and F. petroliphilum stat. nov. Fungal Genetics and Biology, 53: 59-70.
Aoki T, Smith JA, Mount LL, Geiser DM, O'Donnell K. 2013. Fusarium torreyae sp. nov., a pathogen causing canker disease of Florida torreya (Torreya taxifolia), a critically endangered conifer restricted to northern Florida and southwestern Georgia. Mycologia, 105: 312-319.
Geiser DM, Aoki T, Bacon CW, Baker SE, Bhattacharayya MB, Brandt M, Burgess LW, Chulze S, Coleman JJ, Correll JC, Covert SF, Crous PW, Cuomo CA, de Hoog GS, Di Pietro A, Elmer WH, Epstein L, Frandsen RJN, Freeman S, Gagkaeva T, Glenn AE, Gordon TR, Gregory NF, Hammond-Kosack KE, Hanson LE, Jimenez Gasco MM, Kang S, Kistler HC, Kuldau GA, Leslie JF, Logrieco A, Lu G, Lysøe E, Ma L, McCormick SP, Migheli Q, Moretti A, Munaut F, O'Donnell K, Pfenning LH, Ploetz RC, Proctor RH, Rehner SA, Robert VARG, Rooney AP, Salleh B, Scandiani MM, Scauflaire J, Short DPG, Steenkamp ET, Suga H, Summerell BA, Sutton DA, Thrane U, Trail F, van Diepeningen A, VanEtten HD, Viljoen A, Waalwijk C, Ward TJ, Wingfield MJ, Xu J, Yang X, Yli-Mattila T, Zhang N. 2013. LETTER TO THE EDITOR: One Fungus, One Name: Defining the genus Fusarium in a scientifically robust way that preserves longstanding use. Phytopathology, 103: 400-408.
O'Donnell K, Rooney AP, Proctor RH, Brown DW, McCormick SP, Ward TJ, Frandsen RJN, Lysøe E, Rehner SA, Aoki T, Robert VARG, Crous PW, Groenewald JZ, Kang S, Geiser DM. 2013. Phylogenetic analyses of RPB1 and RPB2 support a middle Cretaceous origin for a clade comprising all agriculturally and medically important fusaria. Fungal Genetics and Biology, 52: 20-31.
Rossman AY, Seifert KA, Samuels GJ, Minnis AM, Schroers H-J, Lombard L, Crous PW, Põldmaa K, Cannon PF, Summerbell RC, Geiser DM, Zhuang W, Hirooka Y, Herrera C, Salgado-Salazar C, Chaverri P. 2013. Genera in Bionectriaceae, Hypocreaceae, and Nectriaceae (Hypocreales) proposed for acceptance or rejection. IMA Fungus 4: 41-51.
O'Donnell K, Humber RA, Geiser DM, Kang S, Park B, Robert V, Crous PW, Johnston P, Aoki T, Rooney AP, Renher SA. 2012. Phylogenetic diversity of insecticolous fusaria inferred from multilocus DNA sequence data and their molecular identification via FUSARIUM-ID and Fusarium MLST. Mycologia 104: 427-45.
Van Diepeningen AD, Geiser DM, Guarro J, Sutton DA, Pearlman E, O'Donnell K, Harak H, Summerell BA, Najafzadeh MJ, Brandt ME, Hennequin C, Tortorano AM, Schroers H-J, Buot G, de Hoog GS. 2012. Proposal for a new ISHAM working group on clinical Fusarium. Mycoses 55: 74.
Short DPG, O'Donnell K, Zhang N, Geiser DM. 2011. Widespread occurrence of diverse human pathogenic types of the fungus Fusarium detected in plumbing drains. J. Clin. Microbiol. 49: 4264-4272.
O'Donnell K, Humber RA, Geiser DM, Kang S, Park B, Robert V, Crous PW, Johnston P, Aoki T, Rooney AP, Renher SA. 2011. Phylogenetic diversity of insecticolous fusaria inferred from multilocus DNA sequence data and their molecular identification via FUSARIUM-ID and Fusarium MLST. Mycologia 104: 427-445.
Hawksworth DL and 86 co-authors. 2011. The Amsterdam Declaration on Fungal Nomenclature. IMA Fungus 2: 105-112.
Karthikeyan RS, Leal SM, Prajna NV, Dharmalingam K, Geiser DM, Pearlman E, Lalitha P. 2011. Expression of innate and adaptive human mediators in human corneal tissue infected with Aspergillus or Fusarium. J. Infect. Dis. 204: 942-950.
Nalim FA, Samuels GJ, Wijesundera RL, Geiser DM. 2011. New species of the Fusarium solani species complex derived from perithecia and soil in the New World tropics. Mycologia 103: 1302-1330.
Park B, Park J, Cheong KC, Choi J, Jung K, Kim D, Lee YH, Ward TJ, O'Donnell K, Geiser DM, Kang S. 2011. Cyberinfrastructure for Fusarium: three integrated platforms supporting strain identification, phylogenetics, comparative genomics and knowledge sharing. Nucl. Acids Res. 39: D640-D646.
- Biology and Ecology of Plant-Microbe and Plant-Environment Interactions
- Forest Pathology
- Diseases of Vegetables, Fruits, Mushrooms, Ornamentals, and Turfgrasses
- Fungal Systematics and Evolution
- Microbial Ecology and Population Biology
- Microbial Genomics and Informatics
- Fusarium Research Center
- Microbe-Host Interactions and Ecosystem Effects Faculty
Genetic basis of host adaptation in fungi
- Plant Disease Management and Adaptive Research Faculty
Fusarium symbionts of invasive ambrosia beetles that damage avocado and other woody hosts
- Microbial Genomics, Evolution and Bioinformatics Faculty
Genomic basis of ecological adaptation in Fusarium and other fungi at the chromosomal level; molecular systematics of Fusarium and other fungi
- Microbial Ecology and Population Biology Faculty
Population dynamics of human and plant pathogenic fungi